Skip to main content

Dr. Jeremy Driskell

University Professor - Analytical Chemistry
Office
SLB Science Lab Building 215
Office Hours
Mon. & Wed. 9-10; Tues. 10-11/ or by appt.
  • About
  • Education
  • Awards & Honors
  • Selected Research

Current Courses

CHE 299.004 Independent Honor Study In Chemistry

CHE 499.004 Independent Research For The Master's Thesis

CHE 290.004 Research in Chemistry

CHE 490.004 Research In Chemistry

CHE 215.001 Analytical Chemistry

CHE 216.002 Analytical Chemistry Laboratory

CHE 299.004 Independent Honor Study In Chemistry

CHE 499.004 Independent Research For The Master's Thesis

CHE 290.004 Research in Chemistry

CHE 490.004 Research In Chemistry

Research Interests & Areas

Research in the Driskell group focuses on the development of novel diagnostic and biological assays by interfacing chemistry, nanomaterials, and biology. Work includes both applied research to develop innovative bioanalytical tools, as well as fundamental research to investigate the mechanism of SERS, antibody-antigen binding kinetics, novel ligands, and protein-nanoparticle interactions.

Post-Doc Chemistry

University of Georgia
Athens, GA

Ph D Analytical Chemistry

Iowa State University
Ames, IA

BS Chemistry

Truman State University
Kirksville, MO

Illinois Science and Technology Coalition (ISTC) Researcher to Know

Illinois Science and Technology Coalition (ISTC)
2025

Outstanding University Researcher

Illinois State University
2025

Named University Professor

Illinois State University
2024

Outstanding College Researcher

CAS
2024

Outstanding Reviewers for Analyst in 2019

Royal Society of Chemistry
2020

Outstanding Reviewers for Analyst in 2018

Royal Society of Chemistry
2019

2016 Emerging Investigator by Analyst

2016

ISU Research Initiative Award to Pre-tenure Faculty

2016

2015 Emerging Investigator by Analytical Methods

2015

DOD-DTRA Young Investigator Award

2013

Grants and Contracts

Enzyme-Mediated Site-Specific Conjugation of Antibodies to Nanoparticles
Jeremy Daniel Driskell
NIH-NGMS. September 1 2022 - August 31 2025
RUI: Chemically Modified Enzymes to Control Adsorption on Gold Nanoparticles for Enhanced Structure/Function
Jeremy Daniel Driskell
NSF - MSN. September 1 2022 - August 31 2025
Coupling Raman Spectroscopy with Ambient Sampling, Portable Mass Spectrometry for On-site, High-Throughput Evidence Confirmation on a Single Instrument Platform
Jeremy Daniel Driskell, Christopher Mulligan, Jun-Hyun Kim, Jamie Wieland
NIJ. January 1 2018 - December 31 2019
RUI: Charge Modified Antibody for Robust and Directional Adsorption onto Gold Nanoparticles
Jeremy Daniel Driskell
NSF. September 1 2018 - August 31 2021
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell
Defense Threat Reduction Agency (DTRA). April 2017 - April 2018
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell
Defense Threat Reduction Agency (DTRA). January 17 2015 - January 16 2017
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell
Defense Threat Reduction Agency (DTRA). January 1 2013 - January 16 2015
Standardized Immunogold: A systematic investigation into antibody-gold nanoparticle conjugation
Jeremy Daniel Driskell
New Faculty Iniative Grant. July 1 2012 - June 30 2013
SERS Based Micro-Sensor Arrays for Quantitative miRNAs Detection
Jeremy Daniel Driskell
National Science Foundation. September 1 2011 - August 31 2014

Intellectual Property

Point of need diagnostic system and method
United States 18/018,968
Jeremy Daniel Driskell, Jun-Hyun Kim

Journal Article

Oriented Surface Immobilization of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation for Enhanced Antigen-Binding Capacity.
Emily Beitello, Kwame Osei, T Kobulnicky, Faith Breausche, Jon Friesen, & Jeremy Daniel Driskell
Langmuir : the ACS journal of surfaces and colloids, 41 (16), 10576-10585, (2025), 10.1021/acs.langmuir.5c00656
Antibody-Driven Assembly of Plasmonic Core-Satellites to Increase the Sensitivity of a SERS Vertical Flow Immunoassay.
Eunice Ebbah, Anthony Amissah, Jun-Hyun Kim, & Jeremy Daniel Driskell
ACS sensors, 9 (7), 3496-3501, (2024), 10.1021/acssensors.4c01052
Enhanced Sensitivity and Homogeneity of SERS Signals on Plasmonic Substrate When Coupled to Paper Spray Ionization-Mass Spectrometry
Adewale Adehinmoye, Ebenezer Bondzie, Jeremy Daniel Driskell, Christopher Mulligan, & Jun-Hyun Kim
Chemosensors, 12 (9), 175, (2024)
Immobilization of Thiol-Modified Horseradish Peroxidase on Gold Nanoparticles Enhances Enzyme Stability and Prevents Proteolytic Digestion.
Faith Breausche, A Somerlot, J Walder, Kwame Osei, Samuel Okyema, & Jeremy Daniel Driskell
Langmuir : the ACS journal of surfaces and colloids, 40 (27), 13957-13967, (2024), 10.1021/acs.langmuir.4c01180
Controlled Temporal Release of Serum Albumin Immobilized on Gold Nanoparticles.
Tosin Ogunlusi & Jeremy Daniel Driskell
Langmuir, 39 (10), 3720-3728, (2023), 10.1021/acs.langmuir.2c03429
SERS-based immunoassay on a plasmonic syringe filter for improved sampling and labeling efficiency of biomarkers.
Eunice Ebbah, Anthony Amissah, Jun-Hyun Kim, & Jeremy Daniel Driskell
The Analyst, (2023), 10.1039/d3an01899g
Structure and activity of native and thiolated α-chymotrypsin adsorbed onto gold nanoparticles.
McKenzie Brynne Riley, Evan Strandquist, Chris Weitzel, & Jeremy Daniel Driskell
Colloids and surfaces. B, Biointerfaces, 220, 112867, (2022), 10.1016/j.colsurfb.2022.112867
High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates.
Samuel Okyema, O Awotunde, Tosin Ogunlusi, McKenzie Brynne Riley, & Jeremy Daniel Driskell
Bioconjugate chemistry, 32 (8), 1753-1762, (2021), 10.1021/acs.bioconjchem.1c00261
Probing the Mechanism of Antibody-Triggered Aggregation of Gold Nanoparticles
Samuel Okyema, O Awotunde, Tosin Ogunlusi, McKenzie Brynne Riley, & Jeremy Daniel Driskell
Langmuir, (2021), 10.1021/acs.langmuir.1c00100
Rapid vertical flow immunoassay on AuNP plasmonic paper for SERS-based point of need diagnostics.
Richard Frimpong, W Jang, Jun-Hyun Kim, & Jeremy Daniel Driskell
Talanta, 223 (Pt 2), 121739, (2021), 10.1016/j.talanta.2020.121739
Integrating SERS and PSI-MS with Dual Purpose Plasmonic Paper Substrates for On-Site Illicit Drug Confirmation
Daniel S. Burr, William L. Fatigante, Jemima Lartey, Wongi Jang, Ashley R Stelmack, Noah W. McClurg, Jean Standard, Jamie Wieland, Jun-Hyun Kim, Christopher Mulligan, & Jeremy Daniel Driskell
ANALYTICAL CHEMISTRY, 92 (9), 6676-6683, (2020), 10.1021/acs.analchem.0c00562
Role of Free Thiol on Protein Adsorption to Gold Nanoparticles
Olatunde Awotunde, Samuel Okyem, Rishika Chikoti, & Jeremy Daniel Driskell
LANGMUIR, 36 (31), 9241-9249, (2020), 10.1021/acs.langmuir.0c01550
Antibodies Irreversibly Adsorb to Gold Nanoparticles and Resist Displacement by Common Blood Proteins
Guadalupe Ruiz, Nicki Ryan, Kylie Rutschke, Olatunde Awotunde, & Jeremy Daniel Driskell
Langmuir, (2019), 10.1021/acs.langmuir.9b01900
Sandwiching analytes with structurally diverse plasmonic nanoparticles on paper substrates for surface enhanced Raman spectroscopy
Jemima Lartey, John Harms, Richard Frimpong, Christopher Mulligan, Jeremy Daniel Driskell, & Jun-Hyun Kim
RSC ADVANCES, 9 (56), 32535-32543, (2019), 10.1039/c9ra05399a
pH Impacts the Orientation of Antibody Adsorbed onto Gold Nanoparticles
Guadalupe Ruiz, Kiran Tripathi, Samuel Okyem, & Jeremy Daniel Driskell
BIOCONJUGATE CHEMISTRY, 30 (4), 1182-1191, (2019), 10.1021/acs.bioconjchem.9b00123
Quantifying Bound and Active Antibodies Conjugated to Gold Nanoparticles: A Comprehensive and Robust Approach To Evaluate Immobilization Chemistry
Kiran Tripathi & Jeremy Daniel Driskell
ACS OMEGA, 3 (7), 8253-8259, (2018), 10.1021/acsomega.8b00591
Asymmetrically Functionalized Antibody-Gold Nanoparticle Conjugates to Form Stable Antigen-Assembled Dimers.
A Mandl, Seth L Filbrun, & Jeremy Daniel Driskell
Bioconjugate chemistry, 28, 38-42, (2017), 10.1021/acs.bioconjchem.6b00459
Chemical modification of antibodies enables the formation of stable antibody-gold nanoparticle conjugates for biosensing
Seth L Filbrun, Alexandra B. Filbrun, Francis L. Lovato, Soon H. Oh, Elizabeth A. Driskell, & Jeremy Daniel Driskell
ANALYST, 142 (23), 4456-4467, (2017), 10.1039/c7an01496a
Structural Characterization and Photoluminescence in the Rare Earth-Free Oxy-Fluoride Anti-Perovskites Sr<sub>3-x
Calvin D Quilty, Maxim Avdeev, Jeremy Daniel Driskell, & Eirin Sullivan
Dalton Transactions, 46, 4055-4065, (2017), 10.1039/c7dt00310b
A fluorescence-based method to directly quantify antibodies immobilized on gold nanoparticles.
Seth L Filbrun & Jeremy Daniel Driskell
The Analyst, 141 (12), 3851-7, (2016), 10.1039/c6an00193a
SERS immunoassay based on the capture and concentration of antigen-assembled gold nanoparticles.
A Lopez, F Lovato, S H Oh, Yen Lai, Seth L Filbrun, E A Driskell, & Jeremy Daniel Driskell
Talanta, 146, 388-93, (2016), 10.1016/j.talanta.2015.08.065
Rapid Screening of Antibody-Antigen Binding using Dynamic Light Scattering (DLS) and Gold Nanoparticles
Yen Lai, Sunghyu Koo, Oh Hwan Soon, Driskell A. Driskell, & Jeremy Daniel Driskell
Analytical Methods, (2015), 10.1039/C5AY00674K
Controllable and reversible hot spot formation on silver nanorod arrays.
J L Abell, Jeremy Daniel Driskell, & Y Zhao
Chemical communications, 50 (1), 106-8, (2014), 10.1039/c3cc45899g
Effect of hydration on plasmonic coupling of bioconjugated gold nanoparticles immobilized on a gold film probed by surface-enhanced Raman spectroscopy.
Jeremy Daniel Driskell, C G Larrick, & C Trunell
Langmuir, 30 (22), 6309-13, (2014), 10.1021/la500640q
Accelerated surface-enhanced Raman spectroscopy (SERS)-based immunoassay on a gold-plated membrane.
M A Penn, D M Drake, & Jeremy Daniel Driskell
Analytical chemistry, 85 (18), 8609-17, (2013), 10.1021/ac402101r

Other

Outstanding Reviewers for Analyst in 2019
Hugh Byrne, Lingxin Chen, Yu-Chung Chang, Jeremy Daniel Driskell, Ning Gan, Hideaki Hisamoto, Juewen Liu, Francis Martin, Muhammad Shiddiky, & Chun-yang Zhang
ROYAL SOC CHEMISTRY, 145 (12), 4068-4068, (2020), 10.1039/d0an90052d

Presentations

Enzyme-mediated site-specific immobilization of antibody onto gold nanoparticles
Jeremy Daniel Driskell
SciX, Cincinnati, OH, October 8, 2025
SERS Vertical Flow Immunoassay Leveraging Antibody-Directed Assembly of Plasmonic Particles
Jeremy Daniel Driskell
SciX, Cincinnati, OH, October 7, 2025
SERS-based Vertical Flow Assay Exploiting Plasmonic Paper and Antibody-Directed Assembly of Plasmonic Core-Satellites for Point of Care Diagnostics
Jeremy Daniel Driskell
ACS Spring 2025 National Meeting, San Diego, CA, March 26, 2025
Structure and Activity of Thiolated Enzymes Adsorbed onto Gold Nanoparticles to form Highly Functional Bioconjugates
Jeremy Daniel Driskell
ACS Fall 2023 National Meeting, San Francisco, CA, August 17, 2023
SERS-based Vertical Flow Assay on Plasmonic Paper for Point of Care Diagnostics
Jeremy Daniel Driskell
SciX, Cincinnati, OH, October 3, 2022
Adsorption Behavior of Chemically/Charged Modified Antibody on Gold Nanoparticles
Jeremy Daniel Driskell
ACS Spring 2022 National Meeting, San Diego, CA, March 21, 2022
Investigating the Stability and Orientation of Antibody Adsorbed onto Gold Nanoparticles
Jeremy Daniel Driskell
ACS Spring 2021 National Meeting, Philadelphia, PA, March 23, 2021
Coupling Raman Spectroscopy with Ambient Sampling, Portable Mass Spectrometry for On-site, High-Throughput Evidence Confirmation on a Single Instrumental Platform
Jeremy Daniel Driskell
American Academy of Forensic Sciences (AAFS) Annual Meeting, Anaheim, CA, February 18, 2020
Integrated SERS-PSI-MS Platform Using Gold Nanoparticle-Embedded Paper for Trace Detection of Illegal Drugs
Jeremy Daniel Driskell, C. Mulligan, J.-H. Kim, W. Fatigante, D. Burr, J. Lartey
SciX, Palm Springs, CA, October 14, 2019
Investigating Antibody-Gold Nanoparticle Adsorption Dynamics to Optimize Conjugates for Biosensing
Jeremy Daniel Driskell
SciX, Palm Springs, CA, October 14, 2019
Investigating Adsorption Dynamics of Serum Proteins onto Gold Nanoparticles
Guadalupe Ruiz, Nicki Ryan, Jeremy Daniel Driskell
ISU Research Symposium, Normal, IL, April 5, 2019
Optimization of Plasmonic Papers for Two-Tiered Drug Analysis on a Portable, SERS-PSI-MS Platform
D. Burr, J. Harms, W. Fatigante, J.-H. Kim, C. Mulligan, Jeremy Daniel Driskell
ISU Research Symposium, Normal, IL, April 5, 2019
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell
North Park University, North Park, IL, April 5, 2019
Towards on-site drug evidence confirmation using ambient sampling, portable mass spectrometry
C. Mulligan, W. Fatigante, A. Stelmack, D. Burr, J. Harms, J.-H. Kim, Jeremy Daniel Driskell, J. Wieland
257th ACS National Meeting & Exposition, Orlando, FL, April 2, 2019
Impact of pH on the Orientation of Antibody Adsorbed onto Gold Nanoparticles
Jeremy Daniel Driskell
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Investigating Adsorption Dynamics of Serum Proteins onto Gold Nanoparticles
Guadalupe Ruiz, Nicki Ryan, Jeremy Daniel Driskell
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Sandwich structure of plasmonic paper for surface enhanced Raman spectroscopy
J. Harms, D. Burr, W. Fatigante, C. Mulligan, Jeremy Daniel Driskell, J.-Hy. Kim
257th ACS National Meeting & Exposition, Orlando, FL, March 31, 2019
Optimization of Plasmonic Papers for Two-Tiered Drug Analysis on a Portable, SERS-PSI-MS Platform
D. Burr, J. Harms, W. Fatigante, J.-H. Kim, C. Mulligan, Jeremy Daniel Driskell
Pittcon, Philadelphia, PA, March 18, 2019
An Analytical Strategy to Evaluate and Optimize Antibody-Gold Nanoparticle Conjugation Chemistry
Jeremy Daniel Driskell
SciX, Atlanta, GA, October 23, 2018
Coupling SERS and ambient ionization mass spectrometry with plasmonic paper for on-site, trace analysis of illicit drugs
Jeremy Daniel Driskell
SciX, Atlanta, GA, October 23, 2018
Investigating Antibody Adsorption Dynamics onto Gold Nanoparticles to Form Stable Conjugates for Analysis of Biological Fluids
Jeremy Daniel Driskell
255th ACS National Meeting & Exposition, New Orleans, LA, March 20, 2018
SERS Detection of Avian Influeznza Virus H3 Subtypes using Functionalized Gold Nanoparticles
Jeremy Daniel Driskell
Pittcon, Orlando, FL, March 1, 2018
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell
Illinois Wesleyan University, Bloomington, IL, November 17, 2017
Flow-through Capture Filters for Enhancing Antibody-Antigen Binding Kinetics
Jeremy Daniel Driskell
Defense Threat Reduction Agency Annual Technical Review, Washington D.C., June 21, 2017
Functionalized Gold Nanoparticles for Biosensing with Surface-Enhanced Raman Scattering (SERS)
Jeremy Daniel Driskell
Northern Kentucky University, Covington, KY, April 12, 2017